securities code: 688193 securities abbreviation: rendu biological bulletin number: 2023-017

Shanghai Rendu Biotechnology Co., Ltd.

Announcement on Resignation of Securities Affairs Representative

the company's board of directors and all directors to ensure that the contents of this announcement does not exist any false records, misleading statements or major omissions, and the authenticity, accuracy and completeness of the contents of the legal responsibility.

The board of directors of Shanghai Rendu Biotechnology Co., Ltd. (hereinafter referred to as the "Company") recently received a written resignation report from Mr. Shi Fei, the securities affairs representative. Mr. Shi Fei applied to resign from the company's securities affairs representative for personal reasons. Effective from the date of delivery to the board of directors.

Mr. Shi Fei will not hold any position in the company after his resignation, and his resignation will not affect the normal development of the company's related business. as of the date of disclosure of this announcement, Mr. Shi Fei did not directly hold shares of the company, there is no commitment to be fulfilled and not fulfilled.

Mr. Shi Fei scrupulously and diligently during his tenure in the company. The company and the board of directors express their heartfelt thanks for his contribution to the company during his tenure! In accordance with the "Shanghai Stock Exchange Science and Technology Innovation Board Stock Listing Rules" and other relevant regulations, the company's board of directors will appoint qualified personnel to serve as securities affairs representatives as soon as possible to assist the company's board secretary in his work.

It is hereby announced.

Board of Directors of Shanghai Rendu Biotechnology Co., Ltd.

17 June 2023